A Reduced Exogenous Steroid Taper for Postoperative Brain Tumor Patients-A Case-Control Study.


School of Medicine, University of California San Francisco, San Francisco, California, USA. Electronic address: [Email]


Dexamethasone is a standard treatment for cerebral edema after brain tumor surgery. However, its side effects can negatively impact the quality and safety of care provided to patients. Sparse evidence exists in the literature regarding postoperative steroid dosing to guide clinicians. The objective of this study was to determine if a new reduced exogenous steroid taper (REST) protocol would effectively treat postoperative cerebral edema while reducing the incidence of steroid-related side effects including diabetes, hypertension, and insomnia.


Brain tumor,Dexamethasone,Postoperative cerebral edema,Steroid taper,