A colorimetric and far-red fluorescent probe for rapid detection of bisulfite/sulfite in full water-soluble based on biquinolinium and its applications.

Affiliation

Zhang C(1), Han L(2), Liu Q(1), Liu M(2), Gu B(3), Shen Y(4).
Author information:
(1)Province Engineering Research Center of Electroplating Wastewater Reuse Technology, Hunan Province Cooperative Innovation Center for the Construction & Development of Dongting Lake Ecological Economic Zone, Hunan Provincial Key Laboratory of Water Treatment Functional Materials, College of Chemistry and Materials Engineering, Hunan University of Arts and Science, Changde 415000, PR China.
(2)Key Laboratory of Functional Organometallic Materials of College of Hunan Province, College of Chemistry and Materials Science, Hengyang Normal University, Hengyang 421008, PR China.
(3)Key Laboratory of Functional Organometallic Materials of College of Hunan Province, College of Chemistry and Materials Science, Hengyang Normal University, Hengyang 421008, PR China. Electronic address: [Email]
(4)Province Engineering Research Center of Electroplating Wastewater Reuse Technology, Hunan Province Cooperative Innovation Center for the Construction & Development of Dongting Lake Ecological Economic Zone, Hunan Provincial Key Laboratory of Water Treatment Functional Materials, College of Chemistry and Materials Engineering, Hunan University of Arts and Science, Changde 415000, PR China. Electronic address: [Email]

Abstract

Bisulfite (HSO3-) and sulfite (SO32-) are involved in numerous physiological processes of living systems. However, high levels of these substances are often correlated to many diseases. Herein, we designed and synthesized a simple full water-soluble colorimetric and far-red fluorescent probe (E)-1-methyl-4-(2-(1-methylquinolin-1-ium-3-yl)vinyl)quinolin-1-ium iodide trifluoromethanesulfonate (DQ) for HSO3-/SO32- detection by coupling 1,4-dimethylquinolinium with 3-quinolinium carboxaldehyde for the first time. The probe DQ showed high selectivity for HSO3- detection via a 1,4-nucleophilic addition reaction with distinct color changes from colorless to purple-red and remarkable far-red fluorescence enhancement in pure aqueous solutions. Specifically, the probe displayed a fast response (<15 s) for bisulfite, which renders it suitable for real time detection of HSO3-. Under the optimized conditions, the far-red fluorescence intensity was linear to the concentrations of HSO3- in the range from 0 to 25 μM and the detection limit was as low as 0.11 μM. Additionally, the probe could be applied to sense HSO3- on paper strips, real sample including vermicelli and sugar and image HSO3- in living cells, which indicated that probe DQ has potential application in food samples and living systems.