A deep learning based method for large-scale classification, registration, and clustering of in-situ hybridization experiments in the mouse olfactory bulb.

Affiliation

Bates College, Program in Neuroscience, Lewiston, ME 04240, United States. Electronic address: [Email]

Abstract

The Allen Mouse Brain Atlas allows study of the brain's molecular anatomy at cellular scale, for thousands genes. To fully leverage this resource, one must register histological images of brain tissue - a task made challenging by the brain's structural complexity and heterogeneity, as well as inter-experiment variability.

Keywords

Convolutional neural network,Image processing,Mitral cell,Neuroinformatics,Olfaction,