A personalized approach to the management of VWD.


Division of Hematology/Oncology, London Health Sciences Centre, Department of Medicine, Western University, ON, Canada. Electronic address: [Email]


The goal of treating Von Willebrand Disease (VWD) is to replace deficient or dysfunctional Von Willebrand Factor (VWF) protein. However, the choice of treatment has to be considered carefully in view of patient factors and the unique properties of replacement products. Tailoring a treatment plan to an individual patient's bleeding challenge is an intricate process. This review describes personalization of treatment selection for desmopressin (DDAVP), VWF replacement concentrates, including the newly available recombinant VWF (rVWF) and prophylaxis as a treatment approach in VWD.


Management of von Willebrand Disease,Personalization of von Willebrand Disease,Personalized approach to von Willebrand Disease,Treatment of von Willebrand Disease,

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