A ratiometric fluorescent sensor based on g-CNQDs@Zn-MOF for the sensitive detection of riboflavin via FRET.

Affiliation

Feng S(1), Pei F(1), Wu Y(1), Lv J(1), Hao Q(1), Yang T(2), Tong Z(3), Lei W(4).
Author information:
(1)School of Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China.
(2)School of Chemistry & Environmental Engineering, Jiangsu University of Technology, Changzhou 213001, China.
(3)State Key Laboratory of NBC Protection for Civilian, Beijing 102205, China. Electronic address: [Email]
(4)School of Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China. Electronic address: [Email]

Abstract

A novel ratiometric fluorescent sensor based on Förster resonance energy transfer (FRET) platform was designed for riboflavin (RF) detection. The graphitic carbon nitrides quantum dots - Zn-MOF composite (g-CNQDs@Zn-MOF) was used as the fluorescent probe. In the FRET system, g-CNQDs@Zn-MOF and RF acted as donor and acceptor, respectively. The probe exhibited high sensitivity and good selectivity to RF, and had been successfully used for the detection of RF in milk and vitamin B2 tablets. The detection limit of the sensor was 15 nM. The strategy expanded the application of MOF in sensing filed and provided a new method for the detection of RF.