Adherence to fluid resuscitation guidelines and outcomes in patients with septic shock: Reassessing the "one-size-fits-all" approach.


Icahn School of Medicine at Mount Sinai, New York, NY, United States. Electronic address: [Email]


The Surviving Sepsis Campaign and Centers for Medicare and Medicaid Services (CMS) Severe Sepsis and Septic Shock Management Bundle (SEP-1) recommend rapid crystalloid infusion (≥30 mL/kg) for patients with sepsis-induced hypoperfusion or septic shock. We aimed to assess compliance with this recommendation, factors associated with non-compliance, and how compliance relates to mortality.


CHF,ESRD,Fluid resuscitation,Sepsis Core measures,Septic shock,Severe sepsis,

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