Age-Normative Pathways of Striatal Connectivity Related to Clinical Symptoms in the General Population.

Affiliation

Department of Psychiatry, Zucker Hillside Hospital, Northwell Health System, Glen Oaks, New York; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, New York; Department of Psychiatry, Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York. Electronic address: [Email]

Abstract

Altered striatal development contributes to core deficits in motor and inhibitory control, impulsivity, and inattention associated with attention-deficit/hyperactivity disorder and may likewise play a role in deficient reward processing and emotion regulation in psychosis and depression. The maturation of striatal connectivity has not been well characterized, particularly as it relates to clinical symptomatology.

Keywords

ADHD,Depression,Development,General psychopathology,Psychosis,Striatum,