Comparing drug interaction frequencies of various hepatitis C treatment regimens among monoinfected patients.

Affiliation

Department of Pharmacy, Samuel S. Stratton Veterans Affairs Medical Center, Albany, NY, USA; Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA, USA. Electronic address: [Email]

Abstract

Four regimens are recommended for treating hepatitis C (HCV) genotype 1 infection. Study aims were to (1) compare frequencies of contraindicated drug interactions (XDDIs) when each HCV regimen is added to medication profiles of HCV-monoinfected patients, (2) quantify the proportion of patients with XDDIs to all four regimens and (3) determine covariates independently associated with having a XDDI to all four regimens.

Keywords

Antiviral,Medications,Pharmacoepidemiology,Safety,

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