Does chlorhexidine mouthwash reduce the rate of oral colonization bygram-negative bacteria in patients with chemotherapy? Aplacebo-controlled trial.


Microbiology Laboratory, Department of Medicine and Nutrition, University of Guanajuato, León, Mexico; Research Department, Bajio Regional High Specialty Hospital, Secretariat of Health, León, Mexico. Electronic address: [Email]


The presence of gram-negative bacteria in the oral cavity is an undesirable occurrence in patients undergoing chemotherapy. Our aim was to investigate the antibacterial effect of 0.12% chlorhexidine mouthwash in chemotherapypatients with a randomized, double-blind, placebo-controlled trial. There were no significant differences between oral colonization rates; there may be local factors that interfere with chlorhexidine activity.


Chlorhexidine,Mouthwash,Oral organisms,

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