Facile preparation of Ni nanoparticle embedded on mesoporous carbon nanorods for non-enzymatic glucose detection.

Affiliation

Jia H(1), Shang N(2), Feng Y(1), Ye H(1), Zhao J(1), Wang H(1), Wang C(3), Zhang Y(4).
Author information:
(1)Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Key Laboratory of Analytical Science and Technology of Hebei Province, College of Chemistry and Environmental Science, Institute of Life Science and Green Development, Hebei University, 071002 Baoding, PR China.
(2)College of Science, Hebei Agricultural University, 071001 Baoding, PR China.
(3)College of Science, Hebei Agricultural University, 071001 Baoding, PR China. Electronic address: [Email]
(4)Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Key Laboratory of Analytical Science and Technology of Hebei Province, College of Chemistry and Environmental Science, Institute of Life Science and Green Development, Hebei University, 071002 Baoding, PR China. Electronic address: [Email]

Abstract

Transition metal doped carbon materials are recognized as promising sensing platforms for glucose detection. Herein, a simple strategy involving crystallinity, nanostructure engineering, and pyrolysis was developed for constructing well-defined Ni nanoparticle embedded on nanoporous carbon nanorods (Ni/NCNs). A three-dimensional nickel-based metal-organic framework (Ni-MOF) was used as both a self-sacrificing template and precursor. Due to the synergistic effects between the uniformly dispersed Ni nanoparticles and the nanoporous carbon matrix, the as-prepared Ni/NCNs exhibited remarkable electrochemical activity. The fabricated Ni/NCNs glucose sensor showed excellent electrocatalytic performance with ultra-low limit of detection, wide linear detection ranges, fast response times (within 1.6 s), superior stability, and anti-interference characteristics. Moreover, the Ni/NCNs sensing platform was successfully applied to analyze glucose concentrations in human blood samples. These results showed that Ni/NCNs hold potential applications in developing enzyme-free glucose sensors.