Factors Beyond Lack of Antibody Govern Pulmonary Complications in Primary Antibody Deficiency.


Department of Medicine, Division of Clinical Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA. [Email]


Pulmonary complications occur frequently in primary antibody deficiency (PAD). While the impact of antibody deficiency may appear implicit for certain respiratory infections, immunoglobulin replacement therapy does not completely ameliorate pulmonary complications in PAD. Thus, there may be antibody-independent factors influencing susceptibility to respiratory disease in PAD, but these remain incompletely defined.


Primary antibody deficiency,asthma,common variable immunodeficiency,interstitial lung disease,x-linked agammaglobulinemia,

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