GDF15 reflects beta cell function in obese patients independently of the grade of impairment of glucose metabolism.

Affiliation

Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria. Electronic address: [Email]

Abstract

Growth differentiation factor 15 (GDF15) is a strong predictor of cardiovascular morbidity and mortality found to be both marker and target of impaired glucose metabolism. GDF15 increases following glucose administration and is up-regulated in obesity and diabetes. We investigate here the relationship between GDF15 and beta cell function.

Keywords

Biomarker,Cardiovascular risk marker,Diabetes,Impaired glucose metabolism,Predictor,

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