Germline Genetic Variants in GATA3 and Breast Cancer Treatment Outcomes in SWOG S8897 Trial and the Pathways Study.

Affiliation

Department of Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center, Buffalo, NY. Electronic address: [Email]

Abstract

GATA3 is a critical transcription factor in maintaining the differentiated state of luminal mammary epithelial cells. We sought to determine the prognostic and predictive roles of GATA3 genotypes for breast cancer.

Keywords

Chemotherapy,Pharmacogenetics,Recurrence,SNPs,Survival,

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