Imaging characteristics of BRAF-mutant non-small cell lung cancer by functional class.


Department of Radiology, Massachusetts General Hospital, United States. Electronic address: [Email]


Mutations in the BRAF gene have emerged as a validated molecular target in the treatment of non-small cell lung cancer (NSCLC). These mutations can be classified into three functional classes based on their mechanisms of oncogenesis. The relationship between these functional classes and their imaging features has not been systematically investigated. The goal of this work is to determine if imaging features of the primary tumor and the pattern of metastasis correlate with the functional class of BRAF mutation.


BRAF mutation,Imaging,Lung cancer,Metastasis,Radiology,