Impact of patient-specific morphologies on sinus flow stasis in transcatheter aortic valve replacement: An in vitro study.


Department of Biomedical Engineering, The Ohio State University, Columbus, Ohio; Division of Cardiac Surgery, Department of Surgery, The Ohio State University, Columbus, Ohio. Electronic address: [Email]


The goal of this study is to evaluate how sinus flow patterns after transcatheter aortic valve replacement in realistic representative patient roots vary. Sinus flow can affect transcatheter aortic valve operation and likely leaflet thrombosis occurrence due to stasis and poor washout. How the interaction between transcatheter aortic valve and representative patient aortic roots affects sinus hemodynamics is important to establish for future individualization of transcatheter aortic valve replacement therapy.


TAVR,leaflet thrombosis,patient root,sinus flow,stasis,transcatheter aortic valve,

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