Impaired prefrontal cortex-thalamus pathway in intractable temporal lobe epilepsy with aberrant executive control function: MRI evidence.


Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, PR China; Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics, Beijing, PR China. Electronic address: [Email]


This study aimed to assess structural and functional connectivity alterations of the prefrontal cortex (PFC)-thalamus axis in individuals with unilateral intractable temporal lobe epilepsy (TLE) showing executive control function (ECF) impairment and to explore the potential mechanism.


Executive control function,Functional connectivity,Magnetic resonance imaging,Temporal lobe epilepsy,