Independent Validation of the Hematoma Expansion Prediction Score: A Non-contrast Score Equivalent in Accuracy to the Spot Sign.


Ottawa Stroke Program, Division of Neurology, Department of Medicine (Neurology), University of Ottawa, Rome C2182, The Ottawa Hospital: Civic Campus, 1053 Carling Avenue, Ottawa, ON, K1Y4E9, Canada. [Email]


The computed tomography angiography (CTA) spot sign is widely used to assess the risk of hematoma expansion following acute intracerebral hemorrhage (ICH). However, not all patients can receive intravenous contrast nor are all hospital systems equipped with this technology. We aimed to independently validate the Hematoma Expansion Prediction (HEP) Score, an 18-point non-contrast prediction scale, in an external cohort and compare its diagnostic capability to the CTA spot sign.


Computed tomography,Computed tomography angiography,Hematoma expansion,Intracerebral hemorrhage,Prediction,