Interleukin-33/ST2 Signaling Promotes Hepatocellular Carcinoma Cell Stemness Expansion Through Activating c-Jun N-terminal Kinase Pathway.

Affiliation

Department of Gastroenterology and Hepatology, The First Hospital of Lanzhou University, The First Medical College of Lanzhou University, Lanzhou University, Lanzhou, Gansu, China. Electronic address: [Email]

Abstract

Interleukin-33 (IL-33) has a variety of biological activities in different pathological models. However, the underlying effects of IL-33 on hepatocellular carcinoma (HCC) have not been fully elucidated. Therefore, we focused on investigating the biological effects of IL-33 on HCC stemness expansion.

Keywords

Hepatocellular carcinoma,IL-33,Stemness,c-Jun N-terminal Kinase,

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