Intestinal injury and gut permeability in sickle cell disease.

Affiliation

Division of Hematology and Hemostasis, New York Medical College, 19 Bradhurst Avenue, Suite 2575S, Hawthorne, Valhalla, NY, 10595, USA. [Email]

Abstract

Due to recurrent hypoxia-reperfusion injury induced by vaso-occlusive crises (VOC), patients with sickle cell disease (SCD) may have intestinal injury and increased permeability. These may explain the qualitative and quantitative neutrophil abnormalities observed in these patients.

Keywords

Gut permeability,Intestinal injury,Sickle cell disease,

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