Legionella pneumophila infection-mediated regulation of RICTOR via miR-218 in U937 macrophage cells.

Affiliation

Department of Laboratory and Vascular Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan. Electronic address: [Email]

Abstract

Inhalation of aerosolized Legionella pneumophila, a Gram-negative bacterium, can cause severe pneumonia. During infection, L. pneumophila replicates intracellularly in macrophages. The involvement of host microRNAs (miRNAs) in L. pneumophila infection is not fully understood.

Keywords

Legionella,Macrophage,Rictor,microRNA,

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