Managing Pathologic Scars by Injecting Auto-Cross-linked Hyaluronic Acid: A Preliminary Prospective Clinical Study.


SOD Chirurgia Ricostruttiva e Chirurgia della Mano (Department of Reconstructive Surgery and Hand Surgery), AOU "Ospedali Riuniti", Via Conca, 71, 60126, Ancona, Italy. [Email]


Pathological scars are unattractive and may significantly impair the patient's quality of life. Current treatments provide inconsistent results, and none may be regarded as definitive. Recently, an auto-cross-linked hyaluronic acid (HA) formulation, IAL-SYSTEM ACP, featuring a long residence time and an enhanced safety profile, has been successfully used to prevent surgical adhesions, treat tendon lesions and rejuvenate the face and the décolletage. This study aims to preliminarily investigate whether IAL-SYSTEM ACP may also be effective in treating pathological scars resulting from burns, trauma or iatrogenic causes.


Auto-cross-linked hyaluronic acid,Dermal pliability,Dermal thickness,Hypertrophic scar,IAL-SYSTEM ACP,