Maternal buprenorphine treatment during pregnancy and maternal physiology.


Johns Hopkins University School of Medicine, Johns Hopkins University, Department of Pediatrics, 733 N Broadway, Baltimore, MD, 21205, USA. Electronic address: [Email]


Buprenorphine, used for opioid use disorder (OUD) treatment during pregnancy, provides unknown effects on maternal physiological activity. The primary aim of this report is to document acute effects of buprenorphine administration on indicators of maternal autonomic functioning. Effects of maternal buprenorphine dose and other substance exposures on maternal measures were examined, as were neonatal abstinence syndrome (NAS) outcomes.


Buprenorphine,Heart rate variability,Maternal physiology,Neonatal abstinence syndrome,Nicotine,Skin conductance,

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