Mechanism of gating and partial agonist action in the glycine receptor.

Affiliation

Yu J(1), Zhu H(1), Lape R(2), Greiner T(2), Du J(1), Lü W(1), Sivilotti L(3), Gouaux E(4).
Author information:
(1)Vollum Institute, Oregon Health & Science University, Portland, OR 97239, USA.
(2)Department of Neuroscience, Physiology and Pharmacology, University College London, Medical Sciences Building, Gower Street, London WC1E 6BT, UK.
(3)Department of Neuroscience, Physiology and Pharmacology, University College London, Medical Sciences Building, Gower Street, London WC1E 6BT, UK. Electronic address: [Email]
(4)Vollum Institute, Oregon Health & Science University, Portland, OR 97239, USA; Howard Hughes Medical Institute, Oregon Health & Science University, Portland, OR 97239, USA. Electronic address: [Email]

Abstract

Comment in Trends Pharmacol Sci. 2021 Jul;42(7):507-509.