Paired genomic analysis of squamous cell carcinoma transformed from EGFR-mutated lung adenocarcinoma.

Affiliation

Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address: [Email]

Abstract

Adenocarcinoma (ADC) to squamous cell carcinoma (SCC) transformation (AST) is reported in epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer after tyrosine kinase inhibitor (TKI) failure. However, little is known about the underlying genomic changes during the AST process.

Keywords

Adenocarcinoma,Carcinoma,Epidermal growth factor,Non-small-cell lung,Receptor,Squamous cell,

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