Predictive and modifying factors of bone mineral density decline in patients with COPD.


Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan. Electronic address: [Email]


Various determinants of osteoporosis have been previously identified. However, only a few longitudinal studies have examined related factors. We aimed to investigate factors predicting and modifying rapid decline of bone mineral density in patients with chronic obstructive pulmonary disease.


Bisphosphonate,COPD,Comorbidity,Osteoporosis,Vertebral fracture,