Primary mediastinal germ cell tumors.

Affiliation

Division of Medical Oncology, Fondazione IRCCS Policlinico San Matteo and University of Pavia, Italy. Electronic address: [Email]

Abstract

Germ cell tumors (GCTs) are a group of neoplasms usually arising in the gonads, and very rarely in sites outside the gonads, mainly in the retroperitoneum, the anterior mediastinum, and pineal gland or the coccyx (mainly in childhood). The prognosis of nonseminoma primary mediastinal GCTs (PMGCTs), is considered to be poorer compared to its retroperitoneal or gonadal counterparts and, according to the International Germ Cell Cancer Collaborative Group, it is considered by definition as a "poor risk" disease.

Keywords

Extragonadal Germ Cell Tumor,Primary mediastinal germ cell tumors (PMGCT),Rare diseases,

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