Radiation-induced and neurofibromatosis-associated malignant peripheral nerve sheath tumors (MPNST) have worse outcomes than sporadic MPNST.


Department of Radiation Oncology, Massachusetts General Hospital, Boston, USA. Electronic address: [Email]


Malignant peripheral nerve sheath tumors (MPNST) may be sporadic or associated with neurofibromatosis or prior radiation. MPNST may behave aggressively with a high rate of local recurrence and distant metastasis.


Local control,Malignant peripheral nerve sheath tumor,Neurofibromatosis,Radiation,Survival,