The application of ultrasonic technology in the treatment of organic pollutants in water has attracted more and more attention in recent years. Compared with conventional treatment, ultrasonic treatment is more efficient and time saving. Ultrasonic technology is effective for the degradation of many refractory organic pollutants. In this paper, the principle, influencing factors and various methods of ultrasonic degradation of organic pollutants are studied in view of ultrasonic treatment alone, ultrasound treatment methods combined with biocatalysts, chemical oxidation and adsorption techniques, respectively. In addition, the problems existing in the treatment of organic pollutants in water by ultrasonic technology are analyzed and the development direction is put forward.