Risk factors associated with failure of total ankle arthroplasty: a nationwide cohort study.

Affiliation

Suh DH(#)(1), Han K(#)(2), Lee JW(3), Kim HJ(4), Kim B(2), Koo BM(1), Kim HK(1), Choi GW(5).
Author information:
(1)Department of Orthopaedic Surgery, Korea University Ansan Hospital, 123, Jeokgeum-ro, Danwon-Gu, Ansan-si, Gyeonggi-do, 15355, Republic of Korea.
(2)Department of Statistics and Actuarial Science, Soongsil University, Seoul, Republic of Korea.
(3)Department of Orthopaedic Surgery, College of Medicine, Yonsei University, Seoul, Republic of Korea.
(4)Department of Orthopaedic Surgery, Korea University Guro Hospital, Seoul, Republic of Korea.
(5)Department of Orthopaedic Surgery, Korea University Ansan Hospital, 123, Jeokgeum-ro, Danwon-Gu, Ansan-si, Gyeonggi-do, 15355, Republic of Korea. [Email]
(#)Contributed equally

Abstract

We conducted a nationwide population-based cohort study to identify the risk factors associated with failure of total ankle arthroplasty (TAA). We included 2,914 subjects who underwent primary TAA between January 1, 2010, and December 31, 2016, utilizing the database of the Korean National Health Insurance Service. Failure of TAA was defined as revision TAA or arthrodesis procedures. An increased risk of TAA failure was observed in the < 65 age group versus the ≥ 75 age group [adjusted hazard ratios (aHR) 2.273, 95% confidence interval (CI) 1.223-4.226 in the 60-64 age group; aHR 2.697, 95% CI 1.405-5.178 in the 55-59 age group; aHR 2.281, 95% CI 1.145-4.543 in the 50-54 age group; aHR 2.851, 95% CI 1.311-6.203 in the < 50 age group]. Conversely, the ≥ 65 age group displayed no increase in the risk of TAA failure. The risk of TAA failure was increased in the severely obese group with body mass index (BMI) of ≥ 30 kg/m2 versus the normal BMI group (aHR 1.632; 95% CI 1.036-2.570). This population-based longitudinal study demonstrated that age < 65 years and BMI of ≥ 30 kg/m2 were associated with increased risk of TAA failure.