Sense of Coherence and Quality of Life in Patients Treated with Antivitamin K Oral Anticoagulants: A Cross-Sectional Study.


Anguas-Gracia A(1)(2)(3), Subirón-Valera AB(1)(3)(4), Rodríguez-Roca B(1), Gasch-Gallén Á(1)(5), Antón-Solanas I(1)(5), Urcola-Pardo F(1)(3).
Author information:
(1)Department of Physiatry and Nursing, Faculty of Health Sciences, University of Zaragoza, C/Domingo Miral s/n, 50009 Zaragoza, Spain.
(2)Research Group Safety and Care
(GIISA0021), Institute of Research of Aragón, 50009 Zaragoza, Spain.
(3)Research Group Water and Environmental Health
(B43_20R), University Institute of Research in Environmental Science of Aragón, University of Zaragoza, 50009 Zaragoza, Spain.
(4)Research Group Sector III Healthcare
(GIIS081), Institute of Research of Aragón, 50009 Zaragoza, Spain.
(5)Research Group Nursing Research in Primary Care in Aragón
(GIIS094), Institute of Research of Aragón, 50009 Zaragoza, Spain.


The aim of this study was to analyze the correlation between the participants' self-reported quality of life and their sense of coherence in a sample (n = 85) of patients on treatment with oral antivitamin K anticoagulants. A cross-sectional design was used. The measurement instruments included a questionnaire on sociodemographic variables, the Spanish version of the Abbreviated World Health Organization Quality of Life questionnaire (WHOQOL-BREF), an oral-anticoagulant-treatment-specific quality-of-life questionnaire, and the sense-of-coherence (SOC) scale. We analyzed the correlations between the participants' characteristics and the results from the quality-of-life and SOC scales. Age, level of education, employment status, living arrangement, and treatment length were the determinants of the quality of life in people treated with oral anticoagulants. We found a significant association between the four domains of the WHOQOL-BREF questionnaire and general treatment satisfaction (p < 0.01); no significant correlations were found between the SOC subscales and the oral-anticoagulant-treatment-specific quality of life in our sample. Women had a worse level of self-management than men. Nursing interventions should be tailored to the needs of the populations on treatment with oral anticoagulants in order to facilitate a higher level of self-management.