Single cell sequencing reveals gene expression signatures associated with bone marrow stromal cell subpopulations and time in culture.


Cell Processing Section, Department of Transfusion Medicine, Clinical Center, National Institutes of Health (NIH), 10 Center Drive-MSC-1184, Building 10, Room 3C720, Bethesda, MD, 20892-1184, USA. [Email]


Bone marrow stromal cells (BMSCs) are a heterogeneous population that participates in wound healing, immune modulation and tissue regeneration. Next generation sequencing was used to analyze transcripts from single BMSCs in order to better characterize BMSC subpopulations.


Bone marrow stromal cells,FGFR2,Next generation sequencing,PLAT,Single cell next generation sequencing,