Transcatheter Mitral Valve Replacement with Intrepid.


Division of Cardiac Surgery, Northwestern University Feinberg School of Medicine, Northwestern University, 201 East Huron Street, Suite 11-140, Chicago, IL 60611-2908, USA. Electronic address: [Email]


Transcatheter mitral valve replacement with the Intrepid device is intended for patients who need mitral valve replacement and who are at an increased risk for conventional surgery. The early published results of the early feasibility trial are reviewed as well as device design and the implant procedure. The Apollo trial is reviewed: a randomized trial of the Intrepid device versus conventional surgery including a single arm study for inoperable patients. The mitral valve structure, pathophysiology, and postimplant physiology pose unique hurdles for any transcatheter implant.


Apollo trial,Mitral regurgitation,Mitral valve,Transcatheter mitral valve replacement,