Transdermal buprenorphine patch: Potential for role in management of opioid dependence.


Senior Resident, Department of Psychiatry and National Drug Dependence Treatment Center, All India Institute of Medical Sciences, New Delhi. Electronic address: [Email]


Despite proven clinical utility, use of sublinugual buprenorphine is fraught with issues of potential diversion among patients with opioid dependence. Transdermal buprenorphine patches provide an alternative delivery model that can be utilized to reduce such diversion. This narrative review discusses the transdermal buprenorphine formulations, and its pharmacology, drug interaction and tolerability profile. The studies utilizing buprenorphine transdermal patches in the treatment of opioid dependence are examined, while the potential of using such patches for maintenance treatment of opioid dependence is examined.


Buprenorphine,Opioid dependence,Opioid maintenance,Transdermal buprenorphine,

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