Vitamin D levels in paediatric intensive care unit patients and its relation to severity of illness: An Indian experience.

Affiliation

Kumar D(1), Singh MV(2), Yadav RK(3), Singh DK(4), Singh DK(5), Siddiqui SA(6).
Author information:
(1)Associate Professor, Department of Pediatrics, Uttar Pradesh University of Medical Science, Etawah, India.
(2)Professor and Head, Department of Pediatrics, S.N. Children Hospital, M.L.N. Medical College, Prayagraj, India.
(3)Professor and Head, Department of Pediatrics, Uttar Pradesh University of Medical Science, Etawah, India.
(4)Professor, Department of Pediatrics, FH Medical College, Firozabad, India.
(5)Senior Resident, Department of Pediatrics, Government Medical College, Jalaun, India.
(6)Assistant Professor, Department of Pediatrics, S.N. Children Hospital, M.L.N. Medical College, Prayagraj, India.

Abstract

 Vitamin D deficiency is a common disorder that is associated with morbidity and mortality in the general population. We conducted a cross-sectional study of 384 children admitted to paediatric intensive care to determine its prevalence and association with severity of illness and outcome in critically ill children. The severity of illness was evaluated using the paediatric risk of mortality score (PRISM III), on admission, at 24 and 48 h. Vitamin D deficiency was observed in 175 children (45.6%) and was associated with higher severity of illness, need for mechanical ventilation and increased mortality.