A first step towards building spectral libraries as complementary tools for snake venom proteome/peptidome studies.

Affiliation

Functional Proteomics Laboratory, Department of Science and Technology, Universidade Federal de São Paulo (ICT-UNIFESP), São José dos Campos, SP, Brazil. Electronic address: [Email]

Abstract

Snake venoms are complex mixtures of a large number of distinct proteins and peptides with biological activity. Peptide spectral libraries are compilations of previously identified MS/MS spectra obtained from proteomics experiments. Here we present the generation and use of a Venom Peptidome and a Venom Proteome spectral library for the analysis of venom proteomes and peptidomes from distinct snake species.

Keywords

Database searching,Peptidome,Proteome,Snake venom,Spectral libraries,

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