Aberrant cortical neurodevelopment in major depressive disorder.


Department of General Psychiatry, Center for Psychosocial Medicine, Heidelberg University, Vosstrasse 4, 69115 Heidelberg, Germany. Electronic address: [Email]


There is strong neuroimaging evidence that cortical alterations represent a core pathophysiological feature of major depressive disorder (MDD). Differential contributions of cortical features of neurodevelopmental origin, which may distinctly contribute to MDD vulnerability, disease-onset, or symptom expression, are unclear at present.


Cortex,Cortical thickness,Depression,Gyrification,MRI,Vulnerability,