Acanthosis nigricans in a Chinese girl with FGFR3 K650 T mutation: a case report and literature review.

Affiliation

Department of Endocrinology, Chinese Academy of Medical Sciences and Peking Union Medical College, Peking Union Medical College Hospital, Beijing, China. [Email]

Abstract

Acanthosis nigricans (AN) is a clinical manifestation featured by velvety brown plaques in skin folds that occurs in some hereditary and syndromic disorders. Fibroblast growth factor receptor 3 (FGFR3) mutations have been identified as one of the genetic causes of inherited AN.

Keywords

Acanthosis nigricans,FGFR3,Mutation,