Association between asymmetric dimethylarginine and in-stent restenosis tissue characteristics assessed by optical coherence tomography.

Affiliation

Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; Department of Internal Medicine, School of Medicine, College of Medicine, National Yang Ming University, Taipei, Taiwan, ROC; Department of Health Care Center, Taipei Veterans General Hospital, Taipei, Taiwan, ROC. Electronic address: [Email]

Abstract

Impaired bioavailability of endothelium-derived nitric oxide (NO) and endothelial dysfunction may play a pivotal role in the pathogenesis of in-stent restenosis (ISR) after coronary stenting. We aimed to investigate the relation between asymmetric dimethylarginine (ADMA), an endogenous NO synthase inhibitor, and the ISR lesions tissue characteristics assessed by optical coherence tomography (OCT).

Keywords

Asymmetric dimethylarginine,In-stent restenosis,Neoatherosclerosis,Optical coherence tomography,