Association between serum haptoglobin and carotid arterial functions: usefulness of a targeted metabolomics approach.

Affiliation

Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Clinical Center for Diabetes, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yishan Road, Shanghai, 200233, People's Republic of China. [Email]

Abstract

Serum haptoglobin (Hp) has been closely associated with cardio-cerebrovascular diseases. We investigated a metabolic profile associated with circulating Hp and carotid arterial functions via a targeted metabolomics approach to provide insight into potential mechanisms.

Keywords

Carotid inter-adventitial diameter,Carotid intima-media thickness,Haptoglobin,Metabolites,Non-diabetes mellitus,Type 2 diabetes,