Clinicopathologic significance of LAIR-1 expression in hepatocellular carcinoma.


Pi-wei Institute, Guangzhou University of Chinese Medicine, Guangzhou, PR China. Electronic address: [Email]


Leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1) is an immune inhibitory receptor which is expressed within most types of hematopoietic cells and negatively regulates immune responses. Recently, we found LAIR-1 expression to be present within tumors of nonhematopoietic lineages. However, the roles of LAIR-1 in hepatocellular carcinoma (HCC) have yet to be examined. The purpose of this study was to investigate the expression of LAIR-1 in HCC tissue and assess its clinical significance at this site.


Hepatocelluar carcinoma,LAIR-1,Prognosis,Survival,Tissue microarrays,

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