Comparative evaluation of [18F]DiFA and its analogs as novel hypoxia positron emission tomography and [18F]FMISO as the standard.

Affiliation

Research Center, Nihon Medi-Physics Co., Ltd., 299-0266 Sodegaura, Japan. Electronic address: [Email]

Abstract

Hypoxia, a common feature of most solid tumors, is an important predictor of tumor progression and resistance to radiotherapy. We developed a novel hypoxia imaging probe with optimal biological characteristics for use in clinical settings.

Keywords

Hypoxia,Nitroimidazole,Positron emission tomography,Tumor,

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