Compendium of skin molecular signatures identifies key pathological features associated with fibrosis in systemic sclerosis.

Affiliation

Division of Rheumatology, Department of Internal Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea [Email]

Abstract

Treatment of patients with systemic sclerosis (SSc) can be challenging because of clinical heterogeneity. Integration of genome-scale transcriptomic profiling for patients with SSc can provide insights on patient categorisation and novel drug targets.

Keywords

fibrosis,gene expression profiles,systemic sclerosis,unsupervised clustering,

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