Defining housekeeping genes suitable for RNA-seq analysis of the human allograft kidney biopsy tissue.


Department of Pathology, University of Pittsburgh Medical Center, E737 UPMC-Montefiore Hospital, 3459 Fifth Ave, Pittsburgh, PA, 15213, USA. [Email]


RNA-seq is poised to play a major role in the management of kidney transplant patients. Rigorous definition of housekeeping genes (HKG) is essential for further progress in this field. Using single genes or a limited set HKG is inherently problematic since their expression might be altered by specific diseases in the patients being studied.


Genes with housekeeping functions,Kidney transplantation,RNA-sequencing,