Early seizures and temporal lobe trauma predict post-traumatic epilepsy: A longitudinal study.


David Geffen School of Medicine at UCLA, United States. Electronic address: [Email]


Injury severity after traumatic brain injury (TBI) is a well-established risk factor for the development of post-traumatic epilepsy (PTE). However, whether lesion location influences the susceptibility of seizures and development of PTE longitudinally has yet to be defined. We hypothesized that lesion location, specifically in the temporal lobe, would be associated with an increased incidence of both early seizures and PTE. As secondary analysis measures, we assessed the degree of brain atrophy and functional recovery, and performed a between-group analysis, comparing patients who developed PTE with those who did not develop PTE.


Brain atrophy,Brain trauma,Coma,Post-traumatic epilepsy,Seizures,Status epilepticus,