External validation and recalibration of the Brock model to predict probability of cancer in pulmonary nodules using NLST data.


Department of Radiological Sciences, Medical Imaging Informatics, University of California, Los Angeles, California, USA [Email]


We performed an external validation of the Brock model using the National Lung Screening Trial (NLST) data set, following strict guidelines set forth by the Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis statement. We report how external validation results can be interpreted and highlight the role of recalibration and model updating.


Brock model,external validation,lung cancer,prediction,recalibration,

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