Fisetin rescues retinal functions by suppressing inflammatory response in a DBA/2J mouse model of glaucoma.

Affiliation

Department of Ophthalmology, People's Hospital of Rizhao, No. 126 Tai'an Road, Donggang District, Rizhao, 276800, Shandong, China. [Email]

Abstract

Glaucoma is a common chronic neurodegenerative disease, which could lead to visual loss. In this study, we aimed to investigate whether fisetin, a natural flavone with anti-inflammatory and antioxidant properties, is able to alleviate glaucoma.

Keywords

DBA/2J mouse,Fisetin,Glaucoma,Nuclear factor kappa-B (NF-κB),Retinal ganglion cells (RGCs),

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