Formate metabolism in health and disease.


Cancer Research UK Beatson Institute, Glasgow, UK; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK. Electronic address: [Email]


Formate is a one-carbon molecule at the crossroad between cellular and whole body metabolism, between host and microbiome metabolism, and between nutrition and toxicology. This centrality confers formate with a key role in human physiology and disease that is currently unappreciated.


Cancer,Formate metabolism,Immune system,Neurodegeneration,Obesity,One-carbon-metabolism,

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