GLP-1 receptor agonists do not affect sodium intake: Exploratory analyses from two randomized clinical trials.


Diabetes Center, Department of Internal Medicine, Amsterdam University Medical Center, Amsterdam, The Netherlands. Electronic address: [Email]


Excessive sodium intake, despite current dietary advice, remains a global issue with cardiovascular and renal consequences. The aim of this study was to determine whether glucagon-like peptide receptor agonists (GLP-1 RAs), used as antihyperglycemic agents for type 2 diabetes (T2DM) management, may reduce salt cravings as they are known to reduce hedonic feeding behavior and are involved in sodium homeostasis by increasing renal sodium excretion.


Diet,Feeding behaviour,GLP-1 receptor agonists,Sodium intake,Type 2 diabetes,

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