Genomic resources for the study of echinoderm development and evolution.

Affiliation

Department of Biological Sciences, Carnegie Mellon University, Mellon Institute, Pittsburgh, PA, United States. Electronic address: [Email]

Abstract

Echinoderms are important research models for a wide range of biological questions. In particular, echinoderm embryos are exemplary models for dissecting the molecular and cellular processes that drive development and testing how these processes can be modified through evolution to produce the extensive morphological diversity observed in the phylum. Modern attempts to characterize these processes depend on some level of genomic analysis; from querying annotated gene sets to functional genomics experiments to identify candidate cis-regulatory sequences. Given how essential these data have become, it is important that researchers using available datasets or performing their own genome-scale experiments understand the nature and limitations of echinoderm genomic analyses. In this chapter we highlight the current state of echinoderm genomic data and provide methodological considerations for common approaches, including analysis of transcriptome and functional genomics datasets.

Keywords

Brittle star,Echinoderm,Expression,Gene regulatory network,Genome,Sea cucumber,Sea star,Sea urchin,

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