Glycaemic variability and its association with enteral and parenteral nutrition in critically ill ventilated patients.

Affiliation

Mater Research Institute - The University of Queensland, Aubigny Place, South Brisbane, Australia. Electronic address: [Email]

Abstract

Extremes of dysglycaemia as well as glycaemic variability are associated with excess mortality in critically ill patients. Glycaemic variability is an increasingly important measure of glucose control in the intensive care unit (ICU) due to this association; however, there is limited data pertaining to the relationship between exogenous glucose from nutrition and glycaemic variability and clinical outcomes. The primary aim of this study was to determine if glycaemic variability is associated with an increase in mortality. Secondary objectives were to investigate any factors affecting glycaemic variability, and to characterise the role nutrition, particularly carbohydrate, plays as a contributing factor to glycaemic variability and other clinical outcomes (duration of ventilation and ICU length of stay).

Keywords

Critical care,Enteral,Glucose,Glycaemic variability,Parenteral,

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